Health inequalities in People with seveRe mental Illnesses: Impact of antipsychOtic tReatments and social Inequalities on long Term phYsical health (PRIORITY).

People with severe mental illness (SMI) are at greater risk of developing diabetes, heart disease and strokes. We aim to examine the long-term effect of antipsychotics on these physical health outcomes in people with SMI. Using electronic primary care records, we will analyse long-term changes in antipsychotic prescription patterns. Then, we will compare people’s body weight, blood pressure and cholesterol before and after the initiation of antipsychotic treatment to understand the long-term impact on physical health. Clinical findings will help patients and their doctors understand how antipsychotics can affect physical health in the long term and inform future treatment decisions.

University College London

Keele University

KTH Royal Institute of Technology

University of Aberdeen